Tag: Crystalluria

In the early days of antibiotic use, a significant number of patients on older sulfonamide medications developed renal complications due to crystalluria, a condition where crystals form in the urine. The primary reason for this phenomenon lies in the chemical properties of sulfonamide compounds, which have low solubility, especially under certain physiological conditions. When these drugs are metabolized and excreted by the kidneys, they can precipitate and form crystalline aggregates, leading to irritation, obstruction, and potential kidney damage.

Sulphadimidine is a sulfonamide antibiotic, a class of drugs known for both its therapeutic efficacy and its potential for a wide range of adverse reactions. Understanding **what are the side effects of sulphadimidine injections?** is crucial for anyone involved in its administration, especially given its common use in veterinary medicine. This medication, while effective against bacterial infections, carries risks that must be carefully managed.