What is a G1 Inhibitor? Understanding its Role in Pharmacology
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5 min read
In oncology, the cell cycle is a primary target for drug development, and approximately 9.5% to 73.8% of human cancers exhibit alterations in the G1/S phase cell-cycle pathway, making it an attractive therapeutic target. A **G1 inhibitor** is a type of drug that works by blocking the progression of cells through the critical G1 checkpoint, effectively preventing or slowing uncontrolled cell proliferation. This targeted approach is at the forefront of modern cancer treatment, moving beyond traditional, less specific cytotoxic methods.