Is Omeprazole a CYP1A2 Inhibitor? A Pharmacological Review
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4 min read
Omeprazole is primarily metabolized by the cytochrome P450 system, specifically enzymes CYP2C19 and CYP3A4 [1.3.1, 1.3.3]. The question of whether **is omeprazole a CYP1A2 inhibitor** is complex, as studies show it has a dual, though weak, role as both a weak inhibitor and an inducer of this enzyme [1.2.1, 1.2.2].