A Pharmacist's Perspective on Why No Caffeine With Ivermectin
•
4 min read
Ivermectin is metabolized in the liver primarily by the CYP3A4 enzyme [1.3.3]. Caffeine is also metabolized by cytochrome P450 enzymes, though mainly CYP1A2 [1.4.1]. This overlap raises a critical question for medication safety: **why no caffeine with ivermectin?**