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Tag: Cyp2c9

Explore our medication guides and pharmacology articles within this category.

Does Milk Thistle Interact with Losartan? What Patients Need to Know

4 min read
Research has demonstrated that silymarin, the active compound in milk thistle, can increase exposure to losartan by inhibiting its metabolism. The important question of `Does milk thistle interact with losartan?` therefore requires a nuanced understanding of specific metabolic pathways and potential clinical risks, especially for individuals with certain genetic variations.

What Enzymes Metabolize Aspirin? An Overview of Pharmacological Pathways

4 min read
The well-known anti-inflammatory and antiplatelet drug aspirin (acetylsalicylic acid) has an astonishingly short plasma half-life of just 15 to 20 minutes. This rapid degradation is a direct result of several key enzymes that metabolize aspirin almost immediately upon absorption, converting it into its main active metabolite, salicylic acid, and other excretable compounds.