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Tag: Cyp2c9 inhibition

Explore our medication guides and pharmacology articles within this category.

What Drugs Inhibit CYP2C9? Understanding Drug-Drug Interactions

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4 min read
More than 10% of currently marketed drugs are metabolized by the cytochrome P450 2C9 (CYP2C9) enzyme, making it a critical player in drug metabolism. Understanding what drugs inhibit CYP2C9 is essential for preventing dangerous drug-drug interactions that can lead to adverse effects and potential toxicity.

What happens if CYP2C9 is inhibited? Understanding the Clinical Impact

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4 min read
The enzyme CYP2C9 is involved in the metabolism of approximately 15-20% of all clinically used drugs that undergo breakdown by P450 enzymes [1.10.3, 1.3.3]. So, **what happens if CYP2C9 is inhibited?** Inhibition slows drug metabolism, leading to higher drug levels and a greater risk of toxicity [1.2.1, 1.2.3].