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Tag: Cyp3a4 inhibitor

Explore our medication guides and pharmacology articles within this category.

What is a Common Concern When Taking Erythromycin?

3 min read
Gastrointestinal disturbances are a very common side effect of erythromycin, a macrolide antibiotic first isolated in 1952 [1.2.6, 1.3.3]. So, what is a common concern when taking erythromycin? The main issues are frequent GI upset, serious cardiac risks, and significant drug interactions.

Can you take amiodarone with tacrolimus? Understanding the Major Drug Interaction

4 min read
According to a 2010 case report in the *American Journal of Transplantation*, a drug interaction between amiodarone and tacrolimus led to a sudden and marked QT prolongation in a transplant recipient, demonstrating the severe risks involved. This makes it critically important to understand if and how you can take amiodarone with tacrolimus safely, though the combination is generally avoided.