Tag: Cytoskeleton

Originally isolated from the bark of the Pacific yew tree, Taxol (paclitaxel) is a landmark chemotherapy drug that revolutionized cancer treatment. Its unique mechanism of action involves binding directly to microtubules, disrupting their normal function and arresting the rapid cell division characteristic of cancer. This article explores the precise molecular details of **how does taxol stabilize microtubules** and the consequences for cellular health.

First introduced into clinical ophthalmology in Japan in 2014, a **rock inhibitor** is a class of compounds that targets the Rho/ROCK signaling pathway, a crucial regulator of cellular functions like migration, adhesion, and contraction. This innovative pharmacological approach has broad therapeutic potential by interfering with fundamental cell signaling processes.