Tag: Dantrolene

First introduced in 1967, dantrolene sodium, originally marketed under the brand name Dantrium, is a postsynaptic muscle relaxant used primarily to treat muscle spasticity. When asking, "What is another name for Dantrium?" the answer refers to its generic name, dantrolene, and other brands such as Revonto and Ryanodex.

Revonto is a brand name for the generic medication dantrolene sodium, a direct-acting skeletal muscle relaxant used to treat and prevent malignant hyperthermia (MH). While Revonto is a form of dantrolene, it differs from other brands and the generic equivalent in its specific formulation and reconstitution process.

Dantrolene carries a significant risk of liver damage (hepatotoxicity), with symptomatic hepatitis occurring in some patients. This guide details the populations and conditions for which this muscle relaxant is contraindicated, helping to clarify who should not use dantrolene for safety reasons.

Since the introduction of dantrolene in the 1980s, the mortality rate of malignant hyperthermia (MH) has dramatically decreased from 70–80% to less than 10%. This significant improvement highlights the life-saving role of this unique muscle relaxant, but what does dantrolene do beyond treating this rare emergency?