Tag: Dat

The dopamine transporter (DAT) is the primary protein responsible for clearing dopamine from the synapse, regulating the signal's duration and intensity. A wide range of drugs, both prescribed and illicit, may affect the DAT, altering brain chemistry and influencing a variety of neurological and behavioral functions.

Clinical research has conclusively demonstrated that modafinil significantly increases extracellular dopamine levels in the human brain by blocking the dopamine transporter. The core question, "Is modafinil dopamine or serotonin?", is answered by understanding its distinct, dopamine-centric mechanism and minimal direct action on serotonin pathways.