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Tag: Depolarization

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What is the mechanism of action of depolarizing neuromuscular blockers?

3 min read
Depolarizing neuromuscular blockers have an extremely rapid onset of action, with paralysis occurring within 30 to 60 seconds of intravenous administration. The intricate answer to **what is the mechanism of action of depolarizing neuromuscular blockers?** lies in their unique ability to mimic acetylcholine, which initially excites and then paralyzes muscle fibers.