Which is better, hydrocortisone or Benadryl cream? A guide to topical itch relief
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6 min read
According to clinical studies, there is more evidence supporting the efficacy of hydrocortisone cream for certain itchy skin conditions than for topical antihistamines like Benadryl cream. Deciding which is better, hydrocortisone or Benadryl cream, largely depends on the specific cause of your skin irritation, as these medications work through distinct mechanisms.