Tag: Desipramine

First approved by the FDA in 1964, desipramine is a tricyclic antidepressant that primarily increases norepinephrine levels in the brain to help regulate mood and alleviate depressive symptoms. So, what does desipramine do to the brain to produce these therapeutic effects and influence other neurological functions? It works by altering the activity of several key neurotransmitters.

According to the National Institutes of Health (NIH), desipramine is a tricyclic antidepressant (TCA) that was once widely used but is now less common due to its toxicity and adverse effects. This raises the question: **is desipramine hazardous**? While effective for some, desipramine carries a range of serious risks, including cardiac complications, seizures, and suicidal thoughts, requiring careful medical supervision.

Medication mix-ups account for thousands of emergency room visits annually, underscoring the critical need for accurate pill identification. When you encounter a white pill with 760 on it, careful examination of its shape and any other markings is essential to confirm its identity and purpose. While the most common identification for a specific white, round tablet is Prednisone, this article will walk you through the specifics and detail other potential matches to ensure you have the correct information.

Initially developed in the 1950s, tricyclic antidepressants (TCAs) were some of the first medications used to treat depression, with protriptyline being a unique exception to the class's typical sedative properties. This secondary amine is widely considered the answer to **What is the most activating tricyclic antidepressant?**, offering an energizing effect rather than the typical drowsiness associated with many other TCAs.

Antidepressants increased the risk of suicidal thinking and behavior in short-term studies in children, adolescents, and young adults. So, what is the black box warning on desipramine and what does it mean for patients?

Originally approved by the FDA in 1964 as a tricyclic antidepressant, desipramine (Norpramin) is primarily used to treat major depressive disorder. However, its applications extend beyond depression, encompassing several important off-label uses for various conditions.