Does indomethacin inhibit COX-2? A pharmacological deep dive
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4 min read
As a potent, non-selective nonsteroidal anti-inflammatory drug (NSAID), indomethacin has been in clinical use for decades. But **does indomethacin inhibit COX-2**, or does it exclusively target other inflammatory pathways? The definitive answer is that it inhibits both, affecting the two isoforms of the cyclooxygenase enzyme through its non-selective nature.
