Tag: Dopamine transporter

The dopamine transporter (DAT) is responsible for clearing dopamine from the synapse, but many drugs interfere with this process. In fact, stimulants like cocaine and methylphenidate achieve their effects primarily by blocking the DAT, leading to an amplified dopamine signal.

The dopamine transporter (DAT) is the primary protein responsible for clearing dopamine from the synapse, regulating the signal's duration and intensity. A wide range of drugs, both prescribed and illicit, may affect the DAT, altering brain chemistry and influencing a variety of neurological and behavioral functions.