Does Ozempic wear off during the week? Understanding Semaglutide's Weekly Cycle
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4 min read
Ozempic (semaglutide) has an elimination half-life of approximately one week, a pharmacokinetic property that allows for its once-weekly dosing schedule. Despite this sustained effect, some users feel that Ozempic wears off during the week, experiencing a return of appetite or cravings in the days leading up to their next injection.