Understanding What Is the Dosing Cap for Vancomycin and the Factors That Influence It
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4 min read
While there is no single universal vancomycin dosing cap, modern practice has shifted toward individualized dosing guided by Area Under the Curve (AUC) monitoring to prevent toxicity, with some studies showing an 8% incidence of acute kidney injury with trough-only dosing compared to as low as 0-2% with AUC dosing. This approach helps define safe maximums, which can vary significantly depending on patient-specific factors, the route of administration, and the severity of the infection.
