Can I switch from gabapentin to pregabalin?
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3 min read
Both gabapentin and pregabalin function by binding to the $\alpha_2\delta$ subunit of voltage-gated calcium channels to modulate neurotransmitter release. Given their shared mechanism of action, it is possible for a healthcare provider to manage a switch, but there are important pharmacological and clinical differences to consider when asking, 'Can I switch from gabapentin to pregabalin?'.