Tag: Drowsy antihistamines

First-generation antihistamines cause sedation in 10% to 25% of users due to their ability to enter the central nervous system. This guide explores **which antihistamines make you most sleepy** and the underlying reasons behind their effects, helping you understand the key differences between sedating and non-sedating options.

According to the Mayo Clinic, itching is a common issue caused by various factors, from skin conditions to internal diseases. When looking for instant relief from itching, over-the-counter (OTC) oral antihistamine pills are often the go-to solution, especially for allergy-related causes.