Do opioids stimulate the sympathetic nervous system? An in-depth look
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4 min read
While commonly viewed as nervous system depressants, research reveals a more complex picture, suggesting that opioids can paradoxically increase sympathetic nervous system (SNS) activity through central nervous system pathways. This nuanced relationship means that the effect is not a simple inhibition but a delicate balance dependent on the specific opioid, dosage, and duration of use.