Does spironolactone work without a meal? The critical role of consistency
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4 min read
Research has shown that taking spironolactone with food significantly enhances its absorption, with one study finding absorption nearly doubled compared to an empty stomach. However, the most important factor for effectiveness is maintaining a consistent dosing schedule, regardless of whether you choose to take it with or without a meal. So, **does spironolactone work without a meal**? Yes, but with specific considerations.