Tag: Drug contraindications

According to a 2019 research review in *The Journal of the American Osteopathic Association*, patients taking selective serotonin reuptake inhibitors (SSRIs), including fluoxetine, have a significantly increased risk of internal bleeding when combined with other medications. Knowing what drug should you not take with fluoxetine is crucial for patient safety and avoiding severe health complications.

During 2015–2018, 13.2% of American adults reported using antidepressant medications in the past 30 days [1.3.2]. Understanding **what drugs you can not take while on antidepressants** is critical for safety, as common medications can lead to dangerous interactions.

Approximately 1 in 10,000 people using clobetasol may experience serious side effects, emphasizing the importance of understanding who should not use clobetasol. This potent topical steroid requires careful consideration of its contraindications, potential risks, and specific application instructions before use.

According to prescribing information, tamsulosin should not be used in combination with strong inhibitors of the CYP3A4 enzyme, such as the antifungal medication ketoconazole. This is one of many crucial medication pairings to avoid when you are taking this alpha-blocker commonly prescribed for benign prostatic hyperplasia (BPH).

For some individuals with asthma, certain medications can trigger a dangerous inflammatory response, leading to severe exacerbations. It's crucial to understand **which drug should be avoided in persons with asthma** to prevent these incidents and effectively manage the condition.

According to prescribing information, the combination of selegiline and meperidine has resulted in severe and sometimes fatal adverse reactions. Understanding **what is the interaction between selegiline and meperidine** is critical for patient safety, as this specific drug combination is strictly contraindicated by health authorities worldwide.

While approximately 10% of the U.S. population reports a penicillin allergy, fewer than 1% are found to be truly allergic after evaluation [1.7.1]. Understanding true contraindications is crucial for safe antibiotic use. So, who cannot take amoxicillin?

In 2021, over 70 million gabapentin prescriptions were dispensed in the US, highlighting its widespread use. However, gabapentin is not safe for everyone, particularly those with pre-existing conditions, concurrent medication use, or a history of substance abuse. Understanding the specific risks and contraindications is crucial for patient safety.

Approximately 10% of patients with a history of penicillin allergy were once thought to be at risk for cross-reactivity with cephalosporins like cefdinir, though modern studies suggest this figure is lower, especially for third-generation antibiotics. However, patients with allergies, renal issues, or specific intestinal problems must still exercise caution and often avoid cefdinir.

In a retrospective study on topical lidocaine toxicity, 33.3% of cases presented with seizures [1.7.1]. Knowing where not to put lidocaine cream is crucial for avoiding systemic absorption and severe health risks, as improper application can lead to dangerous consequences [1.4.1].