Is Metronidazole a CYP3A4 Inhibitor? Separating Fact from Common Misconception
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4 min read
While many drug interaction databases warn that metronidazole may inhibit CYP3A4, multiple controlled studies have shown that it is not a clinically significant inhibitor of this enzyme. This widespread misconception, often based on older case reports involving acutely ill patients, conflicts with modern pharmacokinetic evidence.
