Tag: Drug discontinuation

In June 2020, Portola Pharmaceuticals conducted a market withdrawal of Betrixaban (Bevyxxa) for business reasons, not due to specific safety or quality concerns. This article explores the clinical trial data, market challenges, and regulatory hurdles that answer the question: **Why was Betrixaban discontinued?**

According to the FDA, stopping fingolimod (Gilenya) can lead to a rare but severe worsening of multiple sclerosis (MS) disability, a phenomenon known as rebound effect. Therefore, knowing how to stop fingolimod safely is a critical part of managing MS treatment, which must always be done with strict medical oversight.

The diabetes medication albiglutide, once sold under the brand name Tanzeum, was voluntarily withdrawn from the global market by its manufacturer in 2017 due to limited prescribing and declining sales. This confirms the answer to the query: **Is albiglutide available in the US?** is a definitive no, a reality impacting patients and healthcare providers who have since transitioned to newer alternatives.

In 2017, the manufacturer GlaxoSmithKline (GSK) announced the global withdrawal of Tanzeum (albiglutide) from the market. This means that while albiglutide is the generic name for the drug, there is no generic or branded version available today.

In about 50% of patients, acetazolamide can cause tingling or a “pins and needles” sensation [1.2.2]. Knowing when to stop taking acetazolamide is crucial and should always be a decision made in consultation with a healthcare provider to avoid potential complications [1.3.1].

With the median duration of antidepressant use in the United States averaging approximately five years, understanding their long-term effects is critical. This exploration helps patients and healthcare providers weigh the benefits of sustained symptom relief against potential risks like sexual dysfunction, metabolic changes, and cardiovascular concerns.

In the United States, over two million people are addicted to opioids [1.6.3]. Amid this crisis, patients with severe pain face another challenge: Is Dilaudid being discontinued, and what does this mean for jejich pain management?

In 2014, the FDA determined that the brand-name Diamox tablets and intravenous solution were not withdrawn for safety or effectiveness reasons, despite being listed as discontinued. This clarification is crucial for patients asking, 'Is Diamox being discontinued?' because the active ingredient remains widely available.

Dorzolamide, a carbonic anhydrase inhibitor, is a key medication used to control intraocular pressure in patients with glaucoma or ocular hypertension. According to MedlinePlus, it is crucial to continue using dorzolamide as prescribed and never stop without talking to your doctor, as this could lead to optic nerve damage and vision loss.

In 2022, an estimated 9.3 million U.S. adults needed treatment for opioid use disorder (OUD), but only 25.1% received medications for it [1.6.4]. Amid this crisis, many ask: are they discontinuing buprenorphine, a key medication for OUD?