Tag: Drug induced hiccups

Persistent or intractable hiccups that last longer than 48 hours are occasionally an adverse drug reaction. Understanding **what medications can trigger hiccups** is important, as this side effect can be distressing and impact quality of life. Though often transient, medication-induced singultus can become severe, interrupting a patient's sleep, eating, and overall well-being.

In an analysis of over 8 million adverse drug reaction reports, hiccups occurred in about 0.06% of cases [1.7.1]. Yes, the corticosteroid **Can prednisolone cause hiccups?** is a valid question, as it is a recognized, though uncommon, side effect [1.2.3, 1.2.4].

While Topamax (topiramate) is prescribed to millions for epilepsy and migraine prevention, a peculiar question has emerged from clinical observations [1.6.2, 1.6.3]. Does Topamax cause hiccups? For some individuals, this antiepileptic drug has been linked to persistent and even intractable hiccups [1.2.1, 1.3.1].

While millions of people take loratadine to relieve allergy symptoms, few are aware that hiccups are listed as a possible, though uncommon, side effect in clinical trial data. This article explores the relationship between this popular over-the-counter antihistamine and the peculiar occurrence of involuntary diaphragm spasms, explaining why this reaction may happen.