Does kratom cause hyperpigmentation? The link between chronic use and skin discoloration
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4 min read
According to reports, millions of Americans have used kratom, a substance derived from the *Mitragyna speciosa* tree. A rare but increasingly recognized cutaneous side effect associated with chronic, long-term kratom use is hyperpigmentation, a skin discoloration that can manifest as brown, gray, or blue-gray patches. These effects, documented in numerous case reports, highlight a potentially serious dermatological consequence of the unregulated substance.
