Tag: Drug induced lupus

While extremely rare, some reports have associated the antidepressant bupropion, commonly known as Wellbutrin, with the development of drug-induced cutaneous lupus erythematosus (CLE), a condition where the immune system attacks the skin. It is critical for both patients and healthcare providers to understand the context of this rare adverse reaction when considering medication options.

An estimated 15,000–30,000 cases of drug-induced lupus occur annually in the U.S., caused by a variety of medications. Although uncommon, documented case reports and series indicate that **can bupropion trigger lupus**, specifically the less severe cutaneous form of the disease.

Approximately 6–12% of all lupus cases in the United States are estimated to be drug-induced. This phenomenon raises an important question for patients and clinicians alike: **What medications cause a positive ANA?** The answer lies in understanding how certain drugs can trigger the immune system to produce autoantibodies, mimicking autoimmune conditions.

While joint pain (arthralgia) is a rare side effect of omeprazole, occurring in less than 1 in 1,000 people, it is a reported concern, especially with long-term use. Understanding the potential causes can help patients recognize and manage this adverse reaction if it occurs.

Drug-induced lupus erythematosus (DILE) accounts for an estimated 6% to 12% of all lupus cases, with over 100 medications implicated [1.4.3, 1.6.3]. But a question remains for many: **Can levothyroxine trigger lupus**, a condition it's sometimes associated with?

Annually, an estimated 15,000 to 30,000 new cases of drug-induced lupus are diagnosed in the United States, demonstrating that certain drugs can unexpectedly trigger autoimmune disease in susceptible individuals. This phenomenon, known as drug-induced autoimmunity, highlights the complex relationship between pharmacology and the body's immune system.