Tag: Drug induced weight gain

Studies show that about 20% of U.S. adults take at least one medication that can cause weight gain [1.3.1]. When considering which medication is most likely to cause weight gain, certain antipsychotics like clozapine and olanzapine often top the list [1.4.3, 1.4.5].

Studies show that about 80% of patients taking the antipsychotic olanzapine experience a weight increase of 7% or more over their baseline body weight [1.3.3]. If you've asked, 'What drug makes you gain the most weight?', the evidence points strongly toward certain psychiatric medications.