What Is the Most Powerful Sedative in the World?
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5 min read
Carfentanil, a synthetic opioid, is reported to be 10,000 times more potent than morphine and 100 times more potent than fentanyl, making it one of the most powerful sedatives in the world, but it is exclusively for veterinary use in large animals. For humans, the most potent sedative depends heavily on the specific medical context and the definition of 'powerful'. This article explores the most potent sedatives for both animal and human applications, highlighting the critical differences in their potency and safety profiles.