Tag: Dual elimination

Explore our medication guides and pharmacology articles within this category.

Why is ceftriaxone not renally adjusted? Understanding its unique elimination pathway

Oct 13, 2025 •

3 min read

Approximately 40% to 60% of ceftriaxone is cleared by non-renal routes, which is the primary reason why is ceftriaxone not renally adjusted for most patients with kidney impairment, allowing for a standard dosing regimen.

Understanding Pharmacology: How is ceftriaxone cleared?

Oct 12, 2025 •

4 min read

Approximately 33-67% of ceftriaxone is eliminated via the kidneys, while the remainder is cleared through the bile. Understanding **how is ceftriaxone cleared** is crucial due to this unique dual elimination pathway, which provides flexibility in dosing for patients with mild-to-moderate organ dysfunction.