Understanding the Past: Why Was Bromfenac Removed from the Market?
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4 min read
In June 1998, less than a year after its release, the oral formulation of the nonsteroidal anti-inflammatory drug (NSAID) bromfenac, marketed as Duract, was voluntarily withdrawn by its manufacturer. This swift removal was a direct response to post-marketing reports of severe and sometimes fatal liver toxicity in patients, raising significant alarms about drug safety and the limits of labeling warnings.
