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Tag: Ego dissolution

Explore our medication guides and pharmacology articles within this category.

How and What Does 5-MeO-DMT Do to Your Brain?

3 min read
5-MeO-DMT is an atypical psychedelic that shows up to 1,000-fold greater binding affinity for the serotonin 5-HT1A receptor compared to the classic psychedelic target, the 5-HT2A receptor. This unique pharmacological profile is central to understanding what does 5-MeO-DMT do to your brain and how it differs from other hallucinogens.

Pharmacology Explained: What is the most powerful DMT?

4 min read
With potency estimated at 4 to 20 times that of regular DMT, 5-methoxy-N,N-dimethyltryptamine ($5-MeO-DMT$) is widely regarded as what is the most powerful DMT in terms of psychedelic intensity. This naturally occurring and synthetically produced tryptamine has a distinctive pharmacological profile and profound, though brief, effects on consciousness.