Tag: Electrolyte monitoring

Lithium has a narrow therapeutic index, meaning the dose for treatment is close to the dose that causes toxicity. For this reason, knowing what electrolyte do you monitor with lithium is a critical aspect of safe and effective therapy, with sodium being the most important.

According to a 2020 study of heart failure patients, higher doses of spironolactone (50-100 mg) were independently associated with hyponatremia. This highlights the critical question: Can spironolactone cause hyponatremia, and if so, what are the underlying mechanisms and management strategies?