Tag: Endocrine side effects

Endocrine-related adverse events are among the most common complications of immune checkpoint inhibitor (ICI) therapy, occurring in approximately 10% of patients. These immune-related side effects can impact hormone-producing glands throughout the body, necessitating careful monitoring and management alongside a patient's cancer treatment.

While spironolactone is a widely used medication for conditions like heart failure and hypertension, it is also associated with a variety of potential side effects and complications. Understanding **what problems does spironolactone cause?** is crucial for patients and healthcare providers to manage risks and ensure safe and effective treatment.

According to a 2015 study, the use of lithium has been associated with up to a five-fold increase in the risk of developing hypothyroidism. This phenomenon, where specific prescription drugs trigger an underactive thyroid, answers the question, 'what medications cause low thyroid levels?'.

While spironolactone is primarily known for its diuretic and anti-androgenic effects, impacting several hormonal systems, extensive human research has not definitively proven that it causes hyperthyroidism. This article explores the complex relationship between spironolactone and thyroid function, shedding light on the current understanding of its effects on the endocrine system.