Understanding the Action of Metyrosine in Pharmacology
•
4 min read
Metyrosine (Demser), first approved by the FDA in 1979, is an enzyme inhibitor that can reduce catecholamine biosynthesis by as much as 80% in patients with certain tumors. The action of metyrosine is to decrease the production of epinephrine and norepinephrine, thereby mitigating the severe hypertension and other symptoms associated with excess hormone release.