Does Amitriptyline Help with GERD? The Role of Neuromodulators in Reflux
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4 min read
For some patients, traditional treatments like proton pump inhibitors (PPIs) fail to fully alleviate symptoms of gastroesophageal reflux disease (GERD), with studies showing a significant portion of patients have refractory symptoms. This raises the question: **does amitriptyline help with GERD?** For certain patients with persistent pain or esophageal hypersensitivity, the answer is yes, though it is used differently than standard acid suppressants.
