Tag: Esrd

Less than 0.3% of an administered propofol dose is excreted unchanged in the urine [1.3.5]. The crucial question for clinicians remains: **is propofol renally cleared** in a way that affects dosing in patients with kidney disease? This article explores the complex answer.

Patients with end-stage renal disease (ESRD) often take between 5 and 14 different medications daily [1.11.2]. Understanding **what determines if a drug is dialyzable** is critical for safe and effective medication management in this complex patient population [1.11.1].

According to research, hemodialysis can reduce the elimination half-life of cefazolin from over 20 hours to just 3-4 hours, demonstrating that the drug is efficiently removed during the procedure. This significant clearance confirms that cefazolin **does cefazolin dialyzed out** in patients with end-stage renal disease (ESRD), which has crucial implications for dosage management.