Tag: Excipient

Sorbitol, a type of carbohydrate known as a sugar alcohol, is used in thousands of medical and food products for its unique chemical properties. Its diverse functions range from a potent osmotic laxative to a moisture-retaining excipient in medications. Understanding what is the use of sorbitol reveals its crucial but often hidden presence in many everyday items.

First introduced as a pharmaceutical excipient in the 1960s, microcrystalline cellulose (MCC) has become one of the most widely used inactive ingredients in modern medicine due to its multifunctional properties. This white, inert powder is derived from purified wood pulp and is a staple in the manufacturing of tablets, capsules, and other solid dosage forms. The primary purpose of microcrystalline cellulose is to ensure that medications are effective, stable, and easy to manufacture.

Heavy magnesium carbonate is not just a single-use compound; it serves multiple vital roles in the pharmaceutical industry. Known for its higher bulk density compared to its 'light' counterpart, heavy magnesium carbonate is frequently utilized in medicine to provide relief for conditions like acid indigestion and heartburn.

Over 90% of all solid-dose drugs on the market today use microcrystalline cellulose (MCC) as a binding agent. While its widespread use might suggest a direct approval, the regulatory path for a substance like microcrystalline cellulose is different from that of an active drug and depends on its specific application.

Avicel, a brand of microcrystalline cellulose, has been a leading excipient in the pharmaceutical industry for over 60 years. So, what is Avicel used for in tablets? It serves multiple critical functions that ensure a tablet's structural integrity, correct dosage, and proper release of the active drug ingredient.

While many people are familiar with cough suppressants, far fewer know that fendizoate is a key component often used to enhance their efficacy and stability. Fendizoate itself is an inactive salt, acting as a delivery vehicle for active antitussive ingredients like cloperastine.

As a common, FDA-approved inactive ingredient in many medications, crospovidone plays a crucial and benign role in ensuring oral drugs work as intended. Its primary function is to help tablets and capsules break down quickly in the stomach, releasing the active drug for absorption.

According to the U.S. FDA, crospovidone is a common and approved inactive ingredient used in the pharmaceutical industry. This widespread presence in oral medications and dietary supplements often prompts the question: is crospovidone safe to ingest and what is its role?

Originally synthesized to overcome some limitations of its predecessor, povidone, copovidone has emerged as a cornerstone excipient in modern pharmaceutical formulation. This article explores what is the role of copovidone, delving into its multifunctional applications that enhance drug stability, manufacturability, and performance.

As one of the most widely utilized compounds in both consumer and medical products, polyethylene glycol (PEG) serves a surprisingly diverse set of functions in the body. From treating occasional constipation to revolutionizing targeted drug delivery systems, what does PEG do to your body depends entirely on its molecular weight and intended use. Its low toxicity and high water solubility make it an invaluable tool in modern medicine.