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Tag: Exogenous

Explore our medication guides and pharmacology articles within this category.

Does Melatonin Show Up in Your Blood? A Pharmacological Look

4 min read
Melatonin is a hormone produced naturally by the pineal gland to regulate the sleep-wake cycle, and its levels fluctuate predictably throughout a 24-hour period. In addition to natural production, many people use synthetic melatonin supplements to help with sleep issues. Both endogenous (naturally produced) and exogenous (supplemental) melatonin can be detected in your blood, but they produce vastly different blood concentrations and follow different patterns after entering the bloodstream.