Tag: Expensive drugs

As of 2025, the most expensive medication in the U.S. is Lenmeldy, a gene therapy priced at $4.25 million per dose [1.2.7]. This article answers **what is the most expensive medication in the US?** and explores the groundbreaking science and complex economics behind these costly treatments.

Costing $425,000 per eye, Luxturna (voretigene neparvovec-rzyl) is a one-time gene therapy widely recognized as the most expensive eye drug. This revolutionary treatment targets a rare, inherited form of vision loss and represents a significant advancement in the field of ophthalmic medicine.

Before insurance and patient assistance, TAKHZYRO, a prophylactic treatment for hereditary angioedema (HAE), can cost hundreds of thousands of dollars annually. This significant list price is a major concern for patients and healthcare systems alike, leading many to ask: **how much does TAKHZYRO cost?**

With a price tag of **$4.25 million** for a one-time dose, Lenmeldy is currently the most expensive prescription drug in the world [1.2.2, 1.4.1, 1.4.3]. This article explores what the most expensive prescription drug in the world is and the factors driving its multimillion-dollar cost.

With a price tag of $4.25 million per one-time treatment, Lenmeldy, a gene therapy for a rare genetic disorder, holds the record for **what is the most expensive drug ever sold**. This staggering cost for a single dose highlights the unprecedented pricing of modern gene therapies and raises important questions about healthcare affordability and access.

According to a 2024 report, Humira was the costliest drug for self-funded plans in 2023. For many patients, the answer to what is the most expensive drug for rheumatoid arthritis lies within the class of high-cost biologic medications and advanced targeted therapies, which can cost tens of thousands of dollars annually without insurance.