Tag: Extended half life

For people with severe hemophilia A, a lack of the critical blood-clotting protein known as factor VIII can cause severe, spontaneous, and life-threatening bleeding episodes. Consequently, factor 8 is valuable for its indispensable role in restoring the body's ability to form blood clots, a medical advancement that has revolutionized the lives of patients with this rare genetic disorder.

The duration of a factor VIII infusion varies significantly based on the product, with conventional standard half-life (SHL) concentrates lasting approximately 8 to 12 hours in adults due to their relatively short circulating half-life. This differs considerably from newer extended half-life (EHL) treatments, which are engineered to remain active for longer periods and reduce the frequency of infusions.