Tag: Extended release

According to a study published in the *South African Journal of Psychiatry*, Contramyl XR was found to be a clinically effective treatment for Attention Deficit Hyperactivity Disorder (ADHD) in both new and experienced patients. What is Contramyl? It is a brand name for an extended-release form of the central nervous system (CNS) stimulant medication methylphenidate.

Starting in 2020, the U.S. Food and Drug Administration (FDA) initiated recalls for certain batches of extended-release (ER) metformin due to the presence of N-nitrosodimethylamine (NDMA) above acceptable limits. This action led to confusion about why is metformin being taken off the market, but it was a targeted safety measure by manufacturers, not a market-wide ban.

Nifedipine's onset of action varies significantly depending on its formulation, from a rapid 30-45 minutes for immediate-release capsules to a more gradual effect for extended-release tablets. Understanding these differences is crucial for patients, as the choice of formulation dictates how quickly and consistently the medication works to manage conditions like high blood pressure and angina.

With millions of people using Mucinex each year to combat chest congestion, understanding proper usage is critical for safety and effectiveness. The answer to **how often can you take Mucinex per day?** depends heavily on which specific Mucinex product you are using—from immediate-release liquids to 12-hour extended-release tablets.

In August 2024, the FDA approved Crexont® (carbidopa and levodopa) extended-release capsules, marking a significant advancement in Parkinson's disease treatment. This innovation directly addresses motor fluctuations in patients, offering a longer-lasting effect than many existing oral formulations. Here we answer **what is the new drug for carbidopa-levodopa** and explore how this novel therapy is impacting care.

Insomnia is a common side effect of amantadine, affecting some users, which makes administration time a critical factor. The answer to **should amantadine be taken at night?** depends heavily on the specific formulation prescribed.

With a typical half-life of 12-18 hours in healthy adults, understanding **how many hours apart should you take amantadine** is critical for maintaining stable drug levels and maximizing efficacy. Dosing schedules vary significantly based on the specific formulation (immediate- or extended-release) and the condition being treated, from once daily to multiple times a day.

According to a 2017 survey of ADDitude readers, approximately 42% of children and 28% of adults with ADHD have used Concerta, while 32% of children and 33% of adults have used Ritalin. The core question, "Is Concerta better than Ritalin?", has no simple answer, as both medications are effective for managing ADHD symptoms but differ significantly in how they are formulated and affect the body.

For immediate-release Ritalin, peak therapeutic benefit typically occurs within 1 to 2 hours of ingestion. This critical timeframe, however, varies significantly depending on the specific formulation, so knowing how long after taking Ritalin is it most effective is essential for proper symptom management.

As of early 2023, generic versions of the brand-name drug Trokendi XR became commercially available in the United States, providing a lower-cost treatment alternative. These generic versions, known as topiramate extended-release capsules, contain the same active ingredient as the brand-name drug.