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Tag: First dose phenomenon

Explore our medication guides and pharmacology articles within this category.

Understanding Why Is Prazosin Not Preferred for Many Conditions

4 min read
Once a primary treatment for high blood pressure, alpha-blockers like prazosin are now not typically recommended as first-line therapy, largely influenced by the findings of the ALLHAT trial. This significant shift in clinical guidelines highlights **why is prazosin not preferred** over newer alternatives for many conditions, despite its continued utility in specific niche areas like PTSD-related nightmares.