Tag: Folic acid inhibitors

First discovered in the 1930s, sulfonamides were the first widely used synthetic antibiotics. This class of drugs, often referred to as sulfa drugs, initially had a broad spectrum of activity. **What bacteria are sulfonamides effective against?**.

In human medicine, the strategic inhibition of folic acid pathways is a well-established therapeutic strategy, with countless drugs designed for this purpose. Understanding what blocks the production of folic acid reveals the mechanisms behind treatments for cancer, infections, and inflammatory diseases.

Nearly 70 years ago, the first antifolate drug, aminopterin, was used to treat childhood leukemia, revealing the crucial role of folate in cell proliferation. Today, understanding which drug inhibits folic acid is vital in pharmacology, with these medications used for a wide range of conditions from cancer to autoimmune diseases.