Tag: Forskolin

According to scientific studies, the timeframe to see results from forskolin for body composition changes is often assessed over a 12-week period, though outcomes can vary significantly based on individual factors and gender. This variability means there is no single, guaranteed answer to how long it takes to see results from forskolin.

A 2019 study published in *Nutrients* revealed that among users of *Coleus forskohlii* extract, 10.5% reported experiencing adverse events, primarily gastrointestinal symptoms like diarrhea. This highlights the importance of understanding what are the negative effects of forskolin before using the supplement.

Originally used in Ayurvedic medicine for centuries, the compound known as forskolin has a primary pharmacological effect rooted deeply in cellular signaling, specifically by activating the enzyme adenylate cyclase. This unique action elevates cyclic adenosine monophosphate (cAMP) within cells, influencing a wide range of bodily functions, including metabolism, cardiovascular health, and respiratory function.

Originating from the Indian coleus plant (*Coleus forskohlii*), forskolin has a long history in Ayurvedic medicine for treating various conditions. However, its use as a modern supplement necessitates careful consideration of potential risks, particularly understanding what drugs interact with forskolin.

In mice studies, while crude *Coleus forskohlii* extract has been shown to induce fatty liver and hepatotoxicity, the isolated compound forskolin was not responsible for these adverse effects, highlighting a critical distinction for liver health.

Despite some varieties of *Coleus* being anecdotally associated with mild psychoactive effects, decades of pharmacological research confirm that the plant is not a controlled substance or a narcotic. This article investigates the science behind the different species, clarifying their chemical properties and addressing common misinformation surrounding the key term **is coleus a narcotic**.

As a dietary supplement, forskolin lacks significant safety data and is not regulated by the FDA in the same way as prescription drugs. For this reason, anyone considering taking this supplement must understand who should not take forskolin due to health risks, side effects, and potential drug interactions.