Tag: Gaba modulation

Despite occasional online claims, the scientific consensus is that kava's main psychoactive effects are not mediated by the opioid receptor system. A 2001 study on different kava cultivars indicated that while some extracts showed minor binding to mu and delta opioid receptors in vitro, this effect was not the primary mechanism of action and was mostly seen with leaf extracts, not traditional root preparations. So, does kava affect opioid receptors, and what is its true pharmacological profile?

According to the National Institute of Mental Health, Generalized Anxiety Disorder (GAD) affects millions of U.S. adults annually. For those seeking an alternative to traditional treatments, the peptide Selank offers a promising solution, developed in Russia for its potent anti-anxiety and cognitive-enhancing properties.