Tag: Gastrointestinal side effects

While generally considered safe for short-term use, one of the most commonly reported side effects of evening primrose oil (EPO) is gastrointestinal upset [1.3.4]. So, to answer the question, **does evening primrose give you diarrhea?** Yes, it can for some individuals, particularly at high doses [1.2.3].

According to a 2025 study, GLP-1 medications like semaglutide were found to be effective for weight loss in people with inflammatory bowel disease (IBD), with a safety profile comparable to those without IBD. Yet, the question remains: Can you take weight loss injections with Crohn's disease, given its potential for severe gastrointestinal side effects?.

According to one report, up to 40% of patients with gastroesophageal reflux disease (GERD) may also have associated gastroparesis or delayed gastric emptying. This raises a critical question for many: **can long term PPI use cause gastroparesis**? While PPIs are known to slow gastric emptying, medical evidence suggests they typically exacerbate, rather than directly cause, the underlying nerve or muscle damage defining gastroparesis.

As with many nonsteroidal anti-inflammatory drugs (NSAIDs), piroxicam is known to cause gastrointestinal (GI) side effects, with studies indicating a higher risk of complications compared to some alternatives. This article explores the pharmacological reasons behind this, explaining why **piroxicam causes acidity** and other digestive issues, and how to manage the risks.

According to clinical trial data, diarrhea is one of the most common side effects of the antibiotic cefuroxime. This gastrointestinal issue, which can range from mild to severe, is a frequently reported complication for those taking this medication.

Studies show that roughly 20% of patients receiving antibiotics experience one or more adverse effects, with gastrointestinal issues being the most common [1.11.1]. So, if you're wondering, **can azithromycin cause stomach pain?**, the answer is a definitive yes for a notable percentage of users [1.2.1, 1.3.1].

Affecting between 1-5% of users, diarrhea is a less frequently reported side effect of amantadine [1.2.5, 1.3.7]. While not one of the most common adverse effects, the question of 'Does amantadine cause diarrhea?' is a valid concern for patients starting this medication.

In clinical trials, gastrointestinal issues are frequently reported by users of Concerta, with nausea occurring in 12.8% of adult participants [1.6.1]. For those asking, **is Concerta hard on your stomach?**, the answer involves understanding these common but often manageable side effects.

Gastrointestinal issues are among the most common adverse effects of methylphenidate, with studies showing that nausea can affect over 12% of patients and stomach discomfort is also frequently reported. Understanding what the side effects of methylphenidate gastro are is key to managing them effectively.

Studies indicate that piperine, the active component in black pepper, is a potent bioavailability enhancer, but at higher doses, it can lead to adverse effects like gastrointestinal discomfort and complex drug interactions. Understanding **what are the side effects of Piperine** is crucial for anyone considering supplementation.