Tag: Gene expression

First approved by the FDA in 1999 for the treatment of cutaneous T-cell lymphoma (CTCL), bexarotene is a synthetic retinoid with a highly specific mechanism of action. It is considered a 'rexinoid' due to its ability to selectively bind to and activate retinoid X receptors (RXRs).

Over 25 percent of all cancers involve mutations in the chromatin regulatory system, a fact that has opened a new frontier in medicine. The question of **What is a foghorn drug?** can lead to two very different answers: the cutting-edge, targeted cancer therapies being developed by a pharmaceutical company called Foghorn Therapeutics, or a dangerous misidentification with illicit street drugs.

First discovered during Russian military research in the 1970s, a bioregulator peptide is a class of ultra-short peptides (typically 2–7 amino acids) that act as epigenetic switches. These signaling molecules are designed to restore normal function to specific organs and systems, offering a targeted approach to cellular regeneration and aging.