Tag: Genetic testing

According to a 2019 randomized, double-blind, placebo-controlled trial, L-methylfolate showed no significant benefit for core ADHD symptoms in adults. This mixed evidence raises a critical question for many seeking alternative treatments: Is L-methylfolate actually good for ADHD? The answer is nuanced and depends on a person's underlying genetics and treatment goals.

Over 400 different genetic mutations have been identified that can lead to a deficiency of glucocerebrosidase, causing the lysosomal storage disorder known as Gaucher disease. This inherited condition prevents the body from properly breaking down a fatty substance called glucocerebroside, leading to its accumulation in cells and causing a wide range of health problems.

Over 90% of people carry at least one genetic variant that affects how their body processes medication [1.6.4]. If you've ever wondered, 'Why is my body not metabolizing medication?', the answer often lies in a combination of your unique genetics, health, and lifestyle.

Research indicates that over 95% of people have at least one high-risk pharmacogenomic variant, emphasizing the need for a personalized approach to medication. This highlights why understanding **what is the role of pharmacist in pharmacogenomics?** is crucial for advancing precision medicine and ensuring patient safety.

Between 4% and 30% of patients show poor or variable responses to the antiplatelet drug clopidogrel, known by the brand name Plavix, due to genetic variations or other factors. For this reason, healthcare providers can perform specialized genetic and functional blood tests to determine the medication's effectiveness and assess if a patient is experiencing 'Plavix resistance'.

Genetic variations can be responsible for significant variability in individual drug responses. This highlights the critical importance of understanding pharmacogenomics (PGx), but **what is a PHG in pharmacy**, and how does it impact patient care?

Over 90% of people have at least one genetic variation that can influence their response to medication. PGx, or pharmacogenomics, is the study of how an individual's genetic makeup affects their reaction to drugs, helping to move healthcare towards a more personalized approach.