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Tag: Genetic variants

Explore our medication guides and pharmacology articles within this category.

What enzymes metabolize clopidogrel? A closer look at CYP enzymes and drug interactions

3 min read
Approximately 85% of the oral antiplatelet drug clopidogrel is hydrolyzed into an inactive form by esterases, leaving only a fraction to be converted into its active, therapeutic metabolite. A complex enzymatic pathway is responsible for this conversion, making the question of **what enzymes metabolize clopidogrel** critical for understanding its variable efficacy in patients.